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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8328 | STING agonist-1 | G10 | Virus Protease , STING |
STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses. | |||
T11035 | DiABZI STING agonist-1 (Tautomerism) | diABZI STING agonist (Compound 3) | STING |
diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. | |||
T5516 | DiABZI STING agonist-1 trihydrochloride | STING | |
diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist. | |||
T13014L | STING agonist-3 trihydrochloride | STING agonist-3 trihydrochloride (2138299-29-1 free base) | Others |
STING agonist-3 trihydrochloride is a selective and non-nucleotide agonist of small-molecule STING(pEC50 and pEC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatme... | |||
T73746 | DiABZI STING agonist-1 | ||
DiABZI STING Agonist-1 is a selective receptor agonist for the stimulator of interferon genes (STING), demonstrating efficacy with EC50 values of 130 nM and 186 nM in human and mouse models, respectively. | |||
T8798 | MSA-2 | STING | |
MSA-2 is a potent and orally available non-nucleotide STING agonist. | |||
T61043 | STING agonist-7 | ||
STING agonist-7 is an agonist of non-nucleotide STING that binds selectively to mouse STING but not human STING [1]. | |||
T75095 | STING agonist-27 | ||
STING agonist-27 (CF509) is a non-nucleotide, small-molecule agonist of STING, which activates STING and demonstrates activity against SARS-CoV series strains [1]. | |||
T75097 | STING agonist-29 | ||
STING agonist-29 (CF511) is a non-nucleotide small-molecule compound that acts as a STING agonist, effectively activating STING and demonstrating activity against SARS-CoV series strains [1]. | |||
T38159 | STING Agonist 12b | ||
STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 ... | |||
T75161 | STING agonist-31 | ||
STING agonist-31, a potent STING agonist, exhibits EC50 values of 0.24 μM and 39.51 μM for human STING (h-STING) and murine STING (m-STING), respectively, demonstrating significant antitumor efficacy [1]. | |||
T38160 | STING Agonist 1a | ||
STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expres... | |||
T75094 | STING agonist-26 | ||
STING agonist-23 (CF508), a non-nucleotide small-molecule STING agonist, activates STING, thereby enhancing the phosphorylation of STING, TBK1, and IRF3. This activation elevates the production of IFN-β, IL-6, CXCL-10, T... | |||
T75092 | STING agonist-24 | ||
STING agonist-24 (CF504), a non-nucleotide small-molecule STING agonist, activates STING, leading to increased phosphorylation of STING, TBK1, and IRF3. It elevates levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-... | |||
T74268 | STING agonist-13 | ||
STING Agonist-13, a stimulator of interferon genes (STING) agonist, enhances cancer immunity through STING-mediated immune activation. It activates STING downstream signaling to promote type I interferon immune responses... | |||
T82760 | C-di-IMP disodium | Cyclic-di-IMP disodium | STING |
C-di-IMP disodium, a STING agonist, is utilized in tumor research [1]. | |||
T79779 | SAP-04 | STING | |
SAP-04 is a potent, orally active STING agonist exhibiting significant immunomodulatory effects appropriate for cancer therapy [1]. | |||
T74621 | STING agonist-9 | ||
STING Agonist-9 (Compound 45) is a powerful stimulator of the STING pathway, demonstrating potent activity with an EC50 of 1.2 nM against human STING (h-STING) and 32.82 μM against mouse STING (m-STING). It exhibits anti... | |||
T75091 | STING agonist-23 | ||
STING agonist-23 (CF502) is a non-nucleotide, small-molecule stimulator of the STING pathway. Upon activation, it enhances the phosphorylation of STING, TBK1, and IRF3, leading to elevated levels of IFN-β, IL-6, CXCL-10,... | |||
T75090 | STING agonist-22 | ||
STING Agonist-22 (CF501) is a potent non-nucleotide STING agonist that functions as an adjuvant by activating STING to induce the type I interferon (IFN-I) response and the production of proinflammatory cytokines. It enh... |